Vitex agnus-castus L. (chaste berry) or chaste berry extract is a popular herbal remedy used primarily for female reproductive ailments in Anglo-American and European practices.
To date, results from randomized controlled trials have shown significant benefits for Vitex agnus castus in treating premenstrual syndrome, premenstrual dysphoric disorder, and latent hyperprolactinemia.
In all studies, Vitex agnus castus extract is superior to placebo, vitamin B6, and magnesium in improving overall PMS symptoms.
It is also used to relieve menopausal symptoms. In several studies, women report improved menopausal symptoms, including better mood and sleep.